Tamas Kalai Selected Research

HO-3538

9/2006

A novel SOD-mimetic permeability transition inhibitor agent protects ischemic heart by inhibiting both apoptotic and necrotic cell death.

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Tamas Kalai Research Topics

Disease

6	Ischemia 06/2006 - 12/2002
3	Heart Failure 01/2014 - 07/2006
3	Infarction (Infarctions) 09/2006 - 12/2003
2	Breast Neoplasms (Breast Cancer) 08/2021 - 12/2014
2	Hypertension (High Blood Pressure) 01/2017 - 01/2014
2	Hypertrophy 01/2014 - 07/2006
2	Cardiomyopathies (Cardiomyopathy) 10/2011 - 01/2005
2	Reperfusion Injury 09/2006 - 06/2006
2	Myocardial Infarction 07/2006 - 06/2006
1	Triple Negative Breast Neoplasms 08/2021
1	Vascular Remodeling 01/2017
1	Inflammation (Inflammations) 01/2017
1	Neoplasms (Cancer) 12/2014
1	Lung Neoplasms (Lung Cancer) 12/2014
1	Glioblastoma (Glioblastoma Multiforme) 12/2014
1	Wounds and Injuries (Trauma) 09/2006
1	Fibrosis (Cirrhosis) 07/2006
1	Ventricular Remodeling 07/2006
1	Cardiomegaly (Heart Hypertrophy) 07/2006
1	Chest Pain (Chest Pains) 06/2006
1	Angina Pectoris 06/2006
1	Myocardial Ischemia (Ischemic Heart Diseases) 06/2006
1	Cardiotoxicity 01/2005

Drug/Important Bio-Agent (IBA)

6	Poly(ADP-ribose) Polymerase InhibitorsIBA 12/2014 - 01/2004
5	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 12/2014 - 03/2004
4	Pharmaceutical PreparationsIBA 08/2021 - 06/2006
4	Proteins (Proteins, Gene)FDA Link 09/2006 - 12/2002
3	2- ((2- piperidin- 1- ylethyl)thio)quinazolin- 4(3H)- oneIBA 01/2017 - 07/2006
3	EnzymesIBA 01/2014 - 07/2006
3	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2011 - 01/2004
3	AntioxidantsIBA 06/2006 - 11/2003
3	NAD (NADH)IBA 02/2006 - 12/2002
2	pyrrolineIBA 08/2021 - 06/2006
2	Mitogen-Activated Protein KinasesIBA 12/2014 - 07/2006
2	p38 Mitogen-Activated Protein KinasesIBA 12/2014 - 06/2006
2	Phosphotransferases (Kinase)IBA 12/2014 - 10/2011
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2014 - 10/2011
2	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2011 - 01/2005
2	Glycogen Synthase Kinase 3 betaIBA 07/2006 - 02/2006
2	WortmanninIBA 02/2006 - 12/2003
1	nitroxylIBA 08/2021
1	Cytostatic AgentsIBA 08/2021
1	mito-carboxy proxylIBA 08/2021
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2017
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	Oxygen (Dioxygen)IBA 01/2017
1	HO 3089IBA 12/2014
1	Radiation-Sensitizing AgentsIBA 12/2014
1	Protein Isoforms (Isoforms)IBA 01/2014
1	HO-3538IBA 09/2006
1	CalciumIBA 09/2006
1	Glycogen Synthase (Synthase I)IBA 07/2006
1	Protein Kinase C-epsilonIBA 07/2006
1	Protein Kinase CIBA 07/2006
1	CollagenIBA 07/2006
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 07/2006
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 06/2006
1	Trimetazidine (Vastarel)IBA 06/2006
1	Creatine Kinase (Creatine Phosphokinase)IBA 06/2006
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 06/2006
1	Krebs-Henseleit solutionIBA 06/2006
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 02/2006
1	PeroxidesIBA 02/2006
1	Phosphocreatine (Neoton)IBA 02/2006
1	Adenosine Triphosphate (ATP)IBA 02/2006
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 02/2006
1	Free RadicalsIBA 01/2005
1	Adenosine Diphosphate (ADP)IBA 03/2004
1	Purinergic P2 Receptors (ADP Receptor)IBA 03/2004
1	Adenine FDA LinkGeneric 03/2004
1	HO3073IBA 12/2003
1	Mexiletine (Mexitil)FDA LinkGeneric 11/2003
1	Thiobarbituric Acid Reactive SubstancesIBA 12/2002
1	Phosphates (Orthophosphate)IBA 12/2002
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 12/2002
1	6- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA 12/2002
1	thiobarbituric acidIBA 12/2002

Therapy/Procedure

1	Therapeutics 08/2021